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More top hotels in Rochester

  1. Even Hotel Rochester – Mayo Clinic Area by IHG

    105 reviews

    Economical and practical, good sanitary conditions, convenient shuttle bus to the clinic.

    Guest review on Trip.com

    fromUS$107per night
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  2. Hilton Rochester Mayo Clinic Area

    111 reviews

    fromUS$196per night
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  3. Hotel Indigo ROCHESTER – MAYO CLINIC AREA by IHG

    113 reviews

    The staff are friendly, and all the facilities are clean. A more detailed explanation of breakfast would be helpful.

    Guest review on Trip.com

    fromUS$87per night
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  4. Kahler Grand Hotel

    99 reviews

    fromUS$134per night
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  5. AmericInn by Wyndham Rochester Near Mayo Clinic

    100 reviews

    fromUS$76per night
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  6. Holiday Inn Express ROCHESTER SOUTH - MAYO AREA by IHG

    109 reviews

    fromUS$93per night
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  7. Courtyard Rochester Mayo Clinic Area/Saint Marys

    99 reviews

    fromUS$129per night
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  8. Quality Inn Near Medical Center

    95 reviews

    fromUS$55per night
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Indicative lowest prices collected from Trip.com on Sep 26, 2026. The live price depends on your dates and is shown on Trip.com.